Life sciences · Prediction
Risk, three years earlier.
A prediction system for cervical and breast cancer that flags elevated risk up to three years before clinical presentation. It is a risk model rather than a diagnostic, and that distinction decides how it should be used.
What it gives you
A risk stratification for one person at one point in time, on a stated horizon. It is built to change screening interval and follow-up priority. It does not replace a diagnostic pathway and it does not replace histopathology.
What it does not
It does not diagnose cancer, and a raised score does not mean cancer is present. It means look sooner, under the protocol that already governs that population. Any deployment that treats the score as a finding is using it outside what it was designed for, and we say so in the contract.
On the three years
Three years is the far edge of the lead time we have observed, not the typical case. A single maximum is close to useless for planning a programme, so what we share under agreement is the distribution.
The number a programme should ask for
Screening populations have low prevalence. At low prevalence a model can have strong sensitivity and specificity and still produce more false positives than true ones, and every false positive is a person walking into an anxious diagnostic pathway.
So the number that decides whether this helps is positive predictive value at the prevalence of the population you are actually screening. Ask us for it early. We will not lead with a headline figure measured somewhere more flattering.
Where the value sits
Not in finding more cancer. In moving finite screening capacity toward the people most likely to benefit, and lengthening intervals safely for those who are not. That is a programme-level decision, so it needs a named clinical owner on your side before it needs a contract.
Cervical and breast cancer risk, ahead of clinical presentation.
- Output
- A risk stratification on a stated horizon, for use in screening triage and interval setting.
- Not for
- Diagnosis. A raised score is a priority, not a finding.
- Populations
- Stated separately for cervical and for breast. The two are not pooled.
- Deployment
- On-premise or in-country, inside an existing screening programme.
- Ask us for
- Positive predictive value at your population's prevalence, and the lead-time distribution.
- Detail
- Method, validation design and performance data are shared under agreement.
Clinical and screening-programme enquiries.
Study design and performance data are shared with clinical and public-health partners under agreement.